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Proactive for invasion: Reuse of matrix metalloproteinase for structural memory

Migratory cells translocate membrane type-1 matrix metalloproteinase (MT1-MMP) to podosomes or invadosomes to break extracellular matrix barriers. In this issue, El Azzouzi et al. (2016. J. Cell. Biol. http://dx.doi.org/10.1083/jcb.201510043) describe an unexpected function for the MT1-MMP cytoplasm...

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Detalles Bibliográficos
Autores principales: Gucciardo, Erika, Mobashir, Mohammad, Lehti, Kaisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828696/
https://www.ncbi.nlm.nih.gov/pubmed/27069020
http://dx.doi.org/10.1083/jcb.201603066
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author Gucciardo, Erika
Mobashir, Mohammad
Lehti, Kaisa
author_facet Gucciardo, Erika
Mobashir, Mohammad
Lehti, Kaisa
author_sort Gucciardo, Erika
collection PubMed
description Migratory cells translocate membrane type-1 matrix metalloproteinase (MT1-MMP) to podosomes or invadosomes to break extracellular matrix barriers. In this issue, El Azzouzi et al. (2016. J. Cell. Biol. http://dx.doi.org/10.1083/jcb.201510043) describe an unexpected function for the MT1-MMP cytoplasmic domain in imprinting spatial memory for podosome reformation via assembly in membrane islets.
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spelling pubmed-48286962016-10-11 Proactive for invasion: Reuse of matrix metalloproteinase for structural memory Gucciardo, Erika Mobashir, Mohammad Lehti, Kaisa J Cell Biol Reviews Migratory cells translocate membrane type-1 matrix metalloproteinase (MT1-MMP) to podosomes or invadosomes to break extracellular matrix barriers. In this issue, El Azzouzi et al. (2016. J. Cell. Biol. http://dx.doi.org/10.1083/jcb.201510043) describe an unexpected function for the MT1-MMP cytoplasmic domain in imprinting spatial memory for podosome reformation via assembly in membrane islets. The Rockefeller University Press 2016-04-11 /pmc/articles/PMC4828696/ /pubmed/27069020 http://dx.doi.org/10.1083/jcb.201603066 Text en © 2016 Gucciardo et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Gucciardo, Erika
Mobashir, Mohammad
Lehti, Kaisa
Proactive for invasion: Reuse of matrix metalloproteinase for structural memory
title Proactive for invasion: Reuse of matrix metalloproteinase for structural memory
title_full Proactive for invasion: Reuse of matrix metalloproteinase for structural memory
title_fullStr Proactive for invasion: Reuse of matrix metalloproteinase for structural memory
title_full_unstemmed Proactive for invasion: Reuse of matrix metalloproteinase for structural memory
title_short Proactive for invasion: Reuse of matrix metalloproteinase for structural memory
title_sort proactive for invasion: reuse of matrix metalloproteinase for structural memory
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828696/
https://www.ncbi.nlm.nih.gov/pubmed/27069020
http://dx.doi.org/10.1083/jcb.201603066
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