Uracil DNA glycosylase interacts with the p32 subunit of the replication protein A complex to modulate HIV-1 reverse transcription for optimal virus dissemination

BACKGROUND: Through incorporation into virus particles, the HIV-1 Vpr protein participates in the early steps of the virus life cycle by influencing the reverse transcription process. We previously showed that this positive impact on reverse transcription was related to Vpr binding to the uracil DNA...

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Detalles Bibliográficos
Autores principales: Herate, Cecile, Vigne, Clarisse, Guenzel, Carolin A., Lambele, Marie, Rouyez, Marie-Christine, Benichou, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828845/
https://www.ncbi.nlm.nih.gov/pubmed/27068393
http://dx.doi.org/10.1186/s12977-016-0257-x

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