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Single time point comparisons in longitudinal randomized controlled trials: power and bias in the presence of missing data
BACKGROUND: The primary analysis in a longitudinal randomized controlled trial is sometimes a comparison of arms at a single time point. While a two-sample t-test is often used, missing data are common in longitudinal studies and decreases power by reducing sample size. Mixed models for repeated mea...
Autores principales: | Ashbeck, Erin L., Bell, Melanie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828848/ https://www.ncbi.nlm.nih.gov/pubmed/27068578 http://dx.doi.org/10.1186/s12874-016-0144-0 |
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