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DotMapper: an open source tool for creating interactive disease point maps

BACKGROUND: Molecular strain typing of tuberculosis isolates has led to increased understanding of the epidemiological characteristics of the disease and improvements in its control, diagnosis and treatment. However, molecular cluster investigations, which aim to detect previously unidentified cases...

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Detalles Bibliográficos
Autores principales: Smith, Catherine M., Hayward, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828871/
https://www.ncbi.nlm.nih.gov/pubmed/27066780
http://dx.doi.org/10.1186/s12879-016-1475-5
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author Smith, Catherine M.
Hayward, Andrew C.
author_facet Smith, Catherine M.
Hayward, Andrew C.
author_sort Smith, Catherine M.
collection PubMed
description BACKGROUND: Molecular strain typing of tuberculosis isolates has led to increased understanding of the epidemiological characteristics of the disease and improvements in its control, diagnosis and treatment. However, molecular cluster investigations, which aim to detect previously unidentified cases, remain challenging. Interactive dot mapping is a simple approach which could aid investigations by highlighting cases likely to share epidemiological links. Current tools generally require technical expertise or lack interactivity. RESULTS: We designed a flexible application for producing disease dot maps using Shiny, a web application framework for the statistical software, R. The application displays locations of cases on an interactive map colour coded according to levels of categorical variables such as demographics and risk factors. Cases can be filtered by selecting combinations of these characteristics and by notification date. It can be used to rapidly identify geographic patterns amongst cases in molecular clusters of tuberculosis in space and time; generate hypotheses about disease transmission; identify outliers, and guide targeted control measures. CONCLUSIONS: DotMapper is a user-friendly application which enables rapid production of maps displaying locations of cases and their epidemiological characteristics without the need for specialist training in geographic information systems. Enhanced understanding of tuberculosis transmission using this application could facilitate improved detection of cases with epidemiological links and therefore lessen the public health impacts of the disease. It is a flexible system and also has broad international potential application to other investigations using geo-coded health information. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12879-016-1475-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-48288712016-04-13 DotMapper: an open source tool for creating interactive disease point maps Smith, Catherine M. Hayward, Andrew C. BMC Infect Dis Software BACKGROUND: Molecular strain typing of tuberculosis isolates has led to increased understanding of the epidemiological characteristics of the disease and improvements in its control, diagnosis and treatment. However, molecular cluster investigations, which aim to detect previously unidentified cases, remain challenging. Interactive dot mapping is a simple approach which could aid investigations by highlighting cases likely to share epidemiological links. Current tools generally require technical expertise or lack interactivity. RESULTS: We designed a flexible application for producing disease dot maps using Shiny, a web application framework for the statistical software, R. The application displays locations of cases on an interactive map colour coded according to levels of categorical variables such as demographics and risk factors. Cases can be filtered by selecting combinations of these characteristics and by notification date. It can be used to rapidly identify geographic patterns amongst cases in molecular clusters of tuberculosis in space and time; generate hypotheses about disease transmission; identify outliers, and guide targeted control measures. CONCLUSIONS: DotMapper is a user-friendly application which enables rapid production of maps displaying locations of cases and their epidemiological characteristics without the need for specialist training in geographic information systems. Enhanced understanding of tuberculosis transmission using this application could facilitate improved detection of cases with epidemiological links and therefore lessen the public health impacts of the disease. It is a flexible system and also has broad international potential application to other investigations using geo-coded health information. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12879-016-1475-5) contains supplementary material, which is available to authorized users. BioMed Central 2016-04-12 /pmc/articles/PMC4828871/ /pubmed/27066780 http://dx.doi.org/10.1186/s12879-016-1475-5 Text en © Smith and Hayward. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Software
Smith, Catherine M.
Hayward, Andrew C.
DotMapper: an open source tool for creating interactive disease point maps
title DotMapper: an open source tool for creating interactive disease point maps
title_full DotMapper: an open source tool for creating interactive disease point maps
title_fullStr DotMapper: an open source tool for creating interactive disease point maps
title_full_unstemmed DotMapper: an open source tool for creating interactive disease point maps
title_short DotMapper: an open source tool for creating interactive disease point maps
title_sort dotmapper: an open source tool for creating interactive disease point maps
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828871/
https://www.ncbi.nlm.nih.gov/pubmed/27066780
http://dx.doi.org/10.1186/s12879-016-1475-5
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