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Application of surface plasmon resonance imaging to monitoring G protein-coupled receptor signaling and its modulation in a heterologous expression system

BACKGROUND: G protein-coupled receptors (GPCRs) are ubiquitous surface proteins mediating various biological responses and thus, important targets for therapeutic drugs. GPCRs individually produce their own signaling as well as modulate the signaling of other GPCRs. Real-time observation of GPCR sig...

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Detalles Bibliográficos
Autores principales:	Nonobe, Yuki, Yokoyama, Tomoki, Kamikubo, Yuji, Yoshida, Sho, Hisajima, Nozomi, Shinohara, Hiroaki, Shiraishi, Yuki, Sakurai, Takashi, Tabata, Toshihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828886/ https://www.ncbi.nlm.nih.gov/pubmed/27068216 http://dx.doi.org/10.1186/s12896-016-0266-9

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