Cargando…

The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids

Uterine fibroids are benign, smooth muscle tumors that occur in approximately 70%–80% of women by age 50 yr. The cellular and molecular mechanism(s) by which uterine fibroids (UFs) develop are not fully understood. Accumulating evidence demonstrates that several genetic abnormalities, including dele...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Qiwei, Nair, Sangeeta, Laknaur, Archana, Ismail, Nahed, Diamond, Michael P., Al-Hendy, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829092/
https://www.ncbi.nlm.nih.gov/pubmed/26888970
http://dx.doi.org/10.1095/biolreprod.115.134924