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EXD2 promotes homologous recombination by facilitating DNA-end resection

Repair of DNA double strand breaks (DSBs) by homologous recombination (HR) is critical for survival and genome stability of individual cells and organisms, but also contributes to the genetic diversity of species. A critical step in HR is MRN/CtIP-dependent end-resection that generates the 3′ single...

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Detalles Bibliográficos
Autores principales:	Broderick, Ronan, Nieminuszczy, Jadwiga, Baddock, Hannah T., Deshpande, Rajashree, Gileadi, Opher, Paull, Tanya T., McHugh, Peter J, Niedzwiedz, Wojciech
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829102/ https://www.ncbi.nlm.nih.gov/pubmed/26807646 http://dx.doi.org/10.1038/ncb3303

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