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Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice

The aim of this study was to investigate the role of macrophage polarization in aging heart. Macrophage differentiation is pathogenically linked to many inflammatory and immune disorders. It is often preceded by myocardial inflammation, which is characterized by increased cardiac damage and pro-infl...

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Detalles Bibliográficos
Autores principales:	Karuppagounder, Vengadeshprabhu, Giridharan, Vijayasree V., Arumugam, Somasundaram, Sreedhar, Remya, Palaniyandi, Suresh S., Krishnamurthy, Prasanna, Quevedo, Joao, Watanabe, Kenichi, Konishi, Tetsuya, Thandavarayan, Rajarajan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829159/ https://www.ncbi.nlm.nih.gov/pubmed/27070323 http://dx.doi.org/10.1371/journal.pone.0152922

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