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HIV-1 and M-PMV RNA Nuclear Export Elements Program Viral Genomes for Distinct Cytoplasmic Trafficking Behaviors

Retroviruses encode cis-acting RNA nuclear export elements that override nuclear retention of intron-containing viral mRNAs including the full-length, unspliced genomic RNAs (gRNAs) packaged into assembling virions. The HIV-1 Rev-response element (RRE) recruits the cellular nuclear export receptor C...

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Detalles Bibliográficos
Autores principales: Pocock, Ginger M., Becker, Jordan T., Swanson, Chad M., Ahlquist, Paul, Sherer, Nathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829213/
https://www.ncbi.nlm.nih.gov/pubmed/27070420
http://dx.doi.org/10.1371/journal.ppat.1005565