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P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate

Prostate smooth muscle tone and hyperplastic growth are involved in the pathophysiology and treatment of male lower urinary tract symptoms (LUTS). Available drugs are characterized by limited efficacy. Patients’ adherence is particularly low to combination therapies of 5α-reductase inhibitors and α(...

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Detalles Bibliográficos
Autores principales:	Wang, Yiming, Gratzke, Christian, Tamalunas, Alexander, Wiemer, Nicolas, Ciotkowska, Anna, Rutz, Beata, Waidelich, Raphaela, Strittmatter, Frank, Liu, Chunxiao, Stief, Christian G., Hennenberg, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829229/ https://www.ncbi.nlm.nih.gov/pubmed/27071060 http://dx.doi.org/10.1371/journal.pone.0153312

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