Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

Virulence of the most deadly malaria parasite Plasmodium falciparum is linked to the variant surface antigen PfEMP1, which is encoded by about 60 var genes per parasite genome. Although the expression of particular variants has been associated with different clinical outcomes, little is known about...

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Detalles Bibliográficos
Autores principales: Bachmann, Anna, Petter, Michaela, Krumkamp, Ralf, Esen, Meral, Held, Jana, Scholz, Judith A. M., Li, Tao, Sim, B. Kim Lee, Hoffman, Stephen L., Kremsner, Peter G., Mordmüller, Benjamin, Duffy, Michael F., Tannich, Egbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829248/
https://www.ncbi.nlm.nih.gov/pubmed/27070311
http://dx.doi.org/10.1371/journal.ppat.1005538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829248/
https://www.ncbi.nlm.nih.gov/pubmed/27070311
http://dx.doi.org/10.1371/journal.ppat.1005538

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