Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse

Oocyte meiotic progression and maternal-to-zygote transition are accompanied by dynamic epigenetic changes. The functional significance of these changes and the key epigenetic regulators involved are largely unknown. Here we show that Setdb1, a lysine methyltransferase, controls the global level of...

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Detalles Bibliográficos
Autores principales: Kim, Jeesun, Zhao, Hongbo, Dan, Jiameng, Kim, Soojin, Hardikar, Swanand, Hollowell, Debra, Lin, Kevin, Lu, Yue, Takata, Yoko, Shen, Jianjun, Chen, Taiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829257/
https://www.ncbi.nlm.nih.gov/pubmed/27070551
http://dx.doi.org/10.1371/journal.pgen.1005970

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