Cargando…
Cap-dependent translation is mediated by ‘RNA looping’ rather than ‘ribosome scanning’
The 40S ribosomal subunit cannot directly recognize the start codon of eukaryotic mRNAs. Instead, it recognizes the start codon after its association with the 5′-cap structure via translation initiation factors. Base-by-base inspection of the 5′UTR by a scanning ribosome is the generally accepted hy...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829323/ https://www.ncbi.nlm.nih.gov/pubmed/26515582 http://dx.doi.org/10.1080/15476286.2015.1107700 |