Therapeutic Drug Monitoring of Vancomycin in Dermal Interstitial Fluid Using Dissolving Microneedles

Objective: To design an alternative painless method for vancomycin (VCM) monitoring by withdrawing interstitial fluid (ISF) the skin using dissolving microneedles (DMNs) and possibly replace the conventional clinical blood sampling method. Methods: Male Wistar rats were anesthetized with 50 mg/kg so...

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Detalles Bibliográficos
Autores principales: Ito, Yukako, Inagaki, Yuto, Kobuchi, Shinji, Takada, Kanji, Sakaeda, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829539/
https://www.ncbi.nlm.nih.gov/pubmed/27076783
http://dx.doi.org/10.7150/ijms.13601

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