Roles of Circular RNAs in Neurologic Disease

Circular RNAs (circRNAs) are a novel type of endogenous noncoding RNA receiving increasing attention. They have been shown to act as a natural microRNA sponges that repress the activity of corresponding miRNAs by binding with them, thus regulating target genes. Numerous studies have shown that miRNA...

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Detalles Bibliográficos
Autores principales: Shao, Yiye, Chen, Yinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829598/
https://www.ncbi.nlm.nih.gov/pubmed/27147959
http://dx.doi.org/10.3389/fnmol.2016.00025
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author Shao, Yiye
Chen, Yinghui
author_facet Shao, Yiye
Chen, Yinghui
author_sort Shao, Yiye
collection PubMed
description Circular RNAs (circRNAs) are a novel type of endogenous noncoding RNA receiving increasing attention. They have been shown to act as a natural microRNA sponges that repress the activity of corresponding miRNAs by binding with them, thus regulating target genes. Numerous studies have shown that miRNAs are involved in the pathogenesis of neurological diseases. Therefore, circRNAs may act as important regulatory factors in the occurrence and development processes of neurological disease.
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spelling pubmed-48295982016-05-04 Roles of Circular RNAs in Neurologic Disease Shao, Yiye Chen, Yinghui Front Mol Neurosci Neuroscience Circular RNAs (circRNAs) are a novel type of endogenous noncoding RNA receiving increasing attention. They have been shown to act as a natural microRNA sponges that repress the activity of corresponding miRNAs by binding with them, thus regulating target genes. Numerous studies have shown that miRNAs are involved in the pathogenesis of neurological diseases. Therefore, circRNAs may act as important regulatory factors in the occurrence and development processes of neurological disease. Frontiers Media S.A. 2016-04-13 /pmc/articles/PMC4829598/ /pubmed/27147959 http://dx.doi.org/10.3389/fnmol.2016.00025 Text en Copyright © 2016 Shao and Chen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Shao, Yiye
Chen, Yinghui
Roles of Circular RNAs in Neurologic Disease
title Roles of Circular RNAs in Neurologic Disease
title_full Roles of Circular RNAs in Neurologic Disease
title_fullStr Roles of Circular RNAs in Neurologic Disease
title_full_unstemmed Roles of Circular RNAs in Neurologic Disease
title_short Roles of Circular RNAs in Neurologic Disease
title_sort roles of circular rnas in neurologic disease
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829598/
https://www.ncbi.nlm.nih.gov/pubmed/27147959
http://dx.doi.org/10.3389/fnmol.2016.00025
work_keys_str_mv AT shaoyiye rolesofcircularrnasinneurologicdisease
AT chenyinghui rolesofcircularrnasinneurologicdisease

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