Cargando…
Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells
Th2 cells produce Th2 cytokines such as IL-4, IL-5 and IL-13, but repress Th1 cytokine IFNγ. Recent studies have revealed various distinct memory-type Th2 cell subsets, one of which produces a substantial amount of IFNγ in addition to Th2 cytokines, however it remains unclear precisely how these Th2...
Autores principales: | Hosokawa, Hiroyuki, Tanaka, Tomoaki, Endo, Yusuke, Kato, Miki, Shinoda, Kenta, Suzuki, Akane, Motohashi, Shinichiro, Matsumoto, Masaki, Nakayama, Keiichi I., Nakayama, Toshinori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829694/ https://www.ncbi.nlm.nih.gov/pubmed/27053161 http://dx.doi.org/10.1038/ncomms11289 |
Ejemplares similares
-
Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene
por: Yamashita, Masakatsu, et al.
Publicado: (2008) -
Maintenance of memory-type pathogenic Th2 cells in the pathophysiology of chronic airway inflammation
por: Hirahara, Kiyoshi, et al.
Publicado: (2018) -
STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
por: Onodera, Atsushi, et al.
Publicado: (2010) -
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro–T cells
por: Hosokawa, Hiroyuki, et al.
Publicado: (2021) -
Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16
por: Hosokawa, Hiroyuki, et al.
Publicado: (2018)