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Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw

AIM OF THE STUDY: To check the degree of acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw MATERIAL AND METHODS: This study involved 562 women between 20 and 77 years of age, all of...

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Autores principales: Olejniczak, Dominik, Dera, Paulina, Religioni, Urszula, Duda-Zalewska, Aneta, Deptała, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829752/
https://www.ncbi.nlm.nih.gov/pubmed/27095945
http://dx.doi.org/10.5114/wo.2016.58504
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author Olejniczak, Dominik
Dera, Paulina
Religioni, Urszula
Duda-Zalewska, Aneta
Deptała, Andrzej
author_facet Olejniczak, Dominik
Dera, Paulina
Religioni, Urszula
Duda-Zalewska, Aneta
Deptała, Andrzej
author_sort Olejniczak, Dominik
collection PubMed
description AIM OF THE STUDY: To check the degree of acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw MATERIAL AND METHODS: This study involved 562 women between 20 and 77 years of age, all of whom were patients visiting gynaecologists practising in clinics in the City of Warsaw. The studied population was divided into six age categories. The study method was a diagnostic poll conducted with the use of an original questionnaire containing 10 multiple-choice questions. RESULTS: Nearly 70% of the women showed an interest in taking a test to detect predispositions to develop breast and ovarian cancer. More than 10% did not want to take such a test, while every fifth women was undecided. No statistically significant differences between the respondents’ willingness to pay and education were found (p = 0.05). The most frequent answer given by women in all groups was that the amount to pay was too high. Such an answer was given by 52.17% of women with primary education, 65.22% of women with vocational education, 58.61% of women with secondary education, and 41.62% of women with higher education. CONCLUSIONS: Women with a confirmed increased risk of developing breast and/or ovarian cancer due to inter alia the presence of BRCA1 and BRCA2 gene mutations should pay particular attention to 1(st) and 2(nd) level prophylaxis.
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spelling pubmed-48297522016-04-19 Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw Olejniczak, Dominik Dera, Paulina Religioni, Urszula Duda-Zalewska, Aneta Deptała, Andrzej Contemp Oncol (Pozn) Original Paper AIM OF THE STUDY: To check the degree of acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw MATERIAL AND METHODS: This study involved 562 women between 20 and 77 years of age, all of whom were patients visiting gynaecologists practising in clinics in the City of Warsaw. The studied population was divided into six age categories. The study method was a diagnostic poll conducted with the use of an original questionnaire containing 10 multiple-choice questions. RESULTS: Nearly 70% of the women showed an interest in taking a test to detect predispositions to develop breast and ovarian cancer. More than 10% did not want to take such a test, while every fifth women was undecided. No statistically significant differences between the respondents’ willingness to pay and education were found (p = 0.05). The most frequent answer given by women in all groups was that the amount to pay was too high. Such an answer was given by 52.17% of women with primary education, 65.22% of women with vocational education, 58.61% of women with secondary education, and 41.62% of women with higher education. CONCLUSIONS: Women with a confirmed increased risk of developing breast and/or ovarian cancer due to inter alia the presence of BRCA1 and BRCA2 gene mutations should pay particular attention to 1(st) and 2(nd) level prophylaxis. Termedia Publishing House 2016-03-16 2016 /pmc/articles/PMC4829752/ /pubmed/27095945 http://dx.doi.org/10.5114/wo.2016.58504 Text en Copyright © 2016 Termedia http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Olejniczak, Dominik
Dera, Paulina
Religioni, Urszula
Duda-Zalewska, Aneta
Deptała, Andrzej
Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw
title Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw
title_full Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw
title_fullStr Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw
title_full_unstemmed Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw
title_short Acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of Warsaw
title_sort acceptance of, inclination for, and barriers in genetic testing for gene mutations that increase the risk of breast and ovarian cancers among female residents of warsaw
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829752/
https://www.ncbi.nlm.nih.gov/pubmed/27095945
http://dx.doi.org/10.5114/wo.2016.58504
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