DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins

Changes in N-glycosylation of plasma proteins are observed in many types of cancer, nevertheless, few studies suggest the exact mechanism involved in aberrant protein glycosylation. Here we studied the impact of DNA methylation on the N-glycome in the secretome of the HepG2 cell line derived from he...

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Detalles Bibliográficos
Autores principales: Klasić, Marija, Krištić, Jasminka, Korać, Petra, Horvat, Tomislav, Markulin, Dora, Vojta, Aleksandar, Reiding, Karli R., Wuhrer, Manfred, Lauc, Gordan, Zoldoš, Vlatka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829869/
https://www.ncbi.nlm.nih.gov/pubmed/27073020
http://dx.doi.org/10.1038/srep24363

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