Cargando…
p53 activation contributes to patulin-induced nephrotoxicity via modulation of reactive oxygen species generation
Patulin is a major mycotoxin found in fungal contaminated fruits and their derivative products. Previous studies showed that patulin was able to induce increase of reactive oxygen species (ROS) generation and oxidative stress was suggested to play a pivotal role in patulin-induced multiple toxic sig...
Autores principales: | Jin, Huan, Yin, Shutao, Song, Xinhua, Zhang, Enxiang, Fan, Lihong, Hu, Hongbo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829895/ https://www.ncbi.nlm.nih.gov/pubmed/27071452 http://dx.doi.org/10.1038/srep24455 |
Ejemplares similares
-
Combining Patulin with Cadmium Induces Enhanced Hepatotoxicity and Nephrotoxicity In Vitro and In Vivo
por: Cui, Jinling, et al.
Publicado: (2021) -
Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway
por: Zhang, Enxiang, et al.
Publicado: (2016) -
Activation of the IRE1α Arm, but not the PERK Arm, of the Unfolded Protein Response Contributes to Fumonisin B1-Induced Hepatotoxicity
por: Liu, Xiaoyi, et al.
Publicado: (2020) -
Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase
por: Song, Xinhua, et al.
Publicado: (2016) -
Glycycoumarin Sensitizes Liver Cancer Cells to ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin Axis
por: Zhang, Enxiang, et al.
Publicado: (2018)