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Differential expression of the epigenetic methylation-related protein DNMT1 by breast cancer molecular subtype and stromal histology
BACKGROUND: We assessed the expression of methylation-related proteins 5-meC, DNMT1, and ISL-1 in breast cancer and evaluated their relationship to clinicopathological factors. METHODS: Immunohistochemical staining for ER, PR, HER-2, Ki-67, 5-meC, DNMT1, and ISL-1 were performed on 348 breast cancer...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830007/ https://www.ncbi.nlm.nih.gov/pubmed/27071379 http://dx.doi.org/10.1186/s12967-016-0840-x |