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Ectopic expression of a small cell lung cancer transcription factor, INSM1 impairs alveologenesis in lung development

BACKGROUND: Insulinoma associated-1 (INSM1) gene is expressed exclusively in early embryonic neuroendocrine tissues, but has been found highly re-activated in most of the neuroendocrine tumors including small cell lung carcinoma. METHODS: In order to elucidate the functional effects of INSM1 in norm...

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Detalles Bibliográficos
Autores principales:	Chen, Chiachen, Breslin, Mary B., Lan, Michael S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830008/ https://www.ncbi.nlm.nih.gov/pubmed/27072116 http://dx.doi.org/10.1186/s12890-016-0215-3

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