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Safety of targeting tumor endothelial cell antigens
The mechanisms underlying discrimination between “self” and “non-self”, a central immunological principle, require careful consideration in immune oncology therapeutics where eliciting anti-cancer immunity must be weighed against the risk of autoimmunity due to the self origin of tumors. Whole cell...
Autores principales: | Wagner, Samuel C., Riordan, Neil H., Ichim, Thomas E., Szymanski, Julia, Ma, Hong, Perez, Jesus A., Lopez, Javier, Plata-Munoz, Juan J., Silva, Francisco, Patel, Amit N., Kesari, Santosh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830034/ https://www.ncbi.nlm.nih.gov/pubmed/27071457 http://dx.doi.org/10.1186/s12967-016-0842-8 |
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