Cargando…

Higher Initial DNA Damage and Persistent Cell Cycle Arrest after Carbon Ion Irradiation Compared to X-irradiation in Prostate and Colon Cancer Cells

The use of charged-particle beams, such as carbon ions, is becoming a more and more attractive treatment option for cancer therapy. Given the precise absorbed dose-localization and an increased biological effectiveness, this form of therapy is much more advantageous compared to conventional radiothe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suetens, Annelies, Konings, Katrien, Moreels, Marjan, Quintens, Roel, Verslegers, Mieke, Soors, Els, Tabury, Kevin, Grégoire, Vincent, Baatout, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830044/ https://www.ncbi.nlm.nih.gov/pubmed/27148479 http://dx.doi.org/10.3389/fonc.2016.00087

Ejemplares similares

Dose- and time-dependent gene expression alterations in prostate and colon cancer cells after in vitro exposure to carbon ion and X-irradiation
por: Suetens, Annelies, et al.
Publicado: (2015)

Carbon ion irradiation of the human prostate cancer cell line PC3: A whole genome microarray study
por: SUETENS, ANNELIES, et al.
Publicado: (2014)

Persistent Impact of In utero Irradiation on Mouse Brain Structure and Function Characterized by MR Imaging and Behavioral Analysis
por: Verreet, Tine, et al.
Publicado: (2016)

The Combination of Particle Irradiation With the Hedgehog Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration of Cancer Cells Compared to X-Ray Irradiation
por: Konings, Katrien, et al.
Publicado: (2019)

Current Evidence for Developmental, Structural, and Functional Brain Defects following Prenatal Radiation Exposure
por: Verreet, Tine, et al.
Publicado: (2016)

Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose
por: Baselet, Bjorn, et al.
Publicado: (2017)

High-LET Carbon and Iron Ions Elicit a Prolonged and Amplified p53 Signaling and Inflammatory Response Compared to low-LET X-Rays in Human Peripheral Blood Mononuclear Cells
por: Macaeva, Ellina, et al.
Publicado: (2021)

Intestinal mucositis precedes dysbiosis in a mouse model for pelvic irradiation
por: Segers, Charlotte, et al.
Publicado: (2021)

Impact of Particle Irradiation on the Immune System: From the Clinic to Mars
por: Fernandez-Gonzalo, Rodrigo, et al.
Publicado: (2017)

DNA damage and repair: underlying mechanisms leading to microcephaly
por: Ribeiro, Jessica Honorato, et al.
Publicado: (2023)

Limnospira indica PCC 8005 Supplementation Prevents Pelvic Irradiation-Induced Dysbiosis but Not Acute Inflammation in Mice
por: Segers, Charlotte, et al.
Publicado: (2023)

Convergence and divergence between the transcriptional responses to Zika virus infection and prenatal irradiation
por: Quintens, Roel
Publicado: (2017)

Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer’s disease
por: Coninx, Emma, et al.
Publicado: (2020)

Combination Therapy With Charged Particles and Molecular Targeting: A Promising Avenue to Overcome Radioresistance
por: Konings, Katrien, et al.
Publicado: (2020)

Combined Exposure to Simulated Microgravity and Acute or Chronic Radiation Reduces Neuronal Network Integrity and Survival
por: Pani, Giuseppe, et al.
Publicado: (2016)

Fractionated irradiation of MCF7 breast cancer cells rewires a gene regulatory circuit towards a treatment‐resistant stemness phenotype
por: Inalegwu, Auchi, et al.
Publicado: (2022)

Comparison of in vitro scratch wound assay experimental procedures
por: Radstake, Wilhelmina E., et al.
Publicado: (2023)

Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development
por: Quintens, Roel, et al.
Publicado: (2015)

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses
por: Baselet, Bjorn, et al.
Publicado: (2017)

A multidisciplinary approach unravels early and persistent effects of X-ray exposure at the onset of prenatal neurogenesis
por: Verreet, Tine, et al.
Publicado: (2015)

Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry
por: Macaeva, Ellina, et al.
Publicado: (2016)

Spaceflight Stressors and Skin Health
por: Radstake, Wilhelmina E., et al.
Publicado: (2022)

A systems radiation biology approach to unravel the role of chronic low-dose-rate gamma-irradiation in inducing premature senescence in endothelial cells
por: Babini, Gabriele, et al.
Publicado: (2022)

Food Supplements to Mitigate Detrimental Effects of Pelvic Radiotherapy
por: Segers, Charlotte, et al.
Publicado: (2019)

Mitochondrial Metabolism in X-Irradiated Cells Undergoing Irreversible Cell-Cycle Arrest
por: Hirose, Eri, et al.
Publicado: (2023)

Hepatic irradiation persistently eliminates liver resident NK cells
por: Nakano, Ryosuke, et al.
Publicado: (2018)

Rosiglitazone Protects Endothelial Cells From Irradiation-Induced Mitochondrial Dysfunction
por: Baselet, Bjorn, et al.
Publicado: (2020)

Radiobiological risks following dentomaxillofacial imaging: should we be concerned?
por: Belmans, Niels, et al.
Publicado: (2021)

Proceedings: Interaction of X-irradiation and drugs on the activity of membrane bound enzymes.
por: Konings, A. W., et al.
Publicado: (1975)

No defect in G1/S cell cycle arrest in irradiated Li-Fraumeni lymphoblastoid cell lines.
por: Williams, K. J., et al.
Publicado: (1996)

Stem Cells and Irradiation
por: Chapel, Alain
Publicado: (2021)

Gravitational effects on fibroblasts’ function in relation to wound healing
por: Radstake, Wilhelmina E., et al.
Publicado: (2023)

Persistence of Bacteroides ovatus under simulated sunlight irradiation
por: Dong, Shengkun, et al.
Publicado: (2014)

X-irradiation induces acute and early term inflammatory responses in atherosclerosis-prone ApoE(−)/(−) mice and in endothelial cells
por: Ramadan, Raghda, et al.
Publicado: (2021)

While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts
por: Leontieva, Olga V., et al.
Publicado: (2017)

Irradiations of CMS silicon sensors with fast neutrons
por: Assouak, S, et al.
Publicado: (2003)

Post-exposure persistence of nitric oxide upregulation in skin cells irradiated by UV-A
por: Hazell, Gareth, et al.
Publicado: (2022)

The Effects of Combined Exposure to Simulated Microgravity, Ionizing Radiation, and Cortisol on the In Vitro Wound Healing Process
por: Radstake, Wilhelmina E., et al.
Publicado: (2023)

Photocarcinogenesis and persistent hyperplasia in UV-irradiated SENCAR mouse skin.
por: Strickland, P T
Publicado: (1986)

High-Dose Irradiation Induces Cell Cycle Arrest, Apoptosis, and Developmental Defects during Drosophila Oogenesis
por: Shim, Hee Jin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_t446g4i705sbvhep4hroc5fqj9