Cargando…

Dexmedetomidine May Produce Extra Protective Effects on Sepsis-induced Diaphragm Injury

OBJECTIVE: The objective was to evaluate the protective effects of dexmedetomidine (DEX), a selective agonist of α2-adrenergic receptor, on sepsis-induced diaphragm injury and the underlying molecular mechanisms. DATA SOURCES: The data used in this review were mainly from PubMed articles published i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Jin, Li, Shi-Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830324/ https://www.ncbi.nlm.nih.gov/pubmed/25963365 http://dx.doi.org/10.4103/0366-6999.156808

Ejemplares similares

Protective Effect of Dexmedetomidine on Endotoxin-Induced Acute Lung Injury in Rats
por: Meng, Peng Z., et al.
Publicado: (2018)

Effects of Dexmedetomidine on Diaphragm Activity Measured by Ultrasonography in Spontaneously Breathing Patients
por: Yun, Hye Joo, et al.
Publicado: (2022)

The Role of Oxidative Stress in Decreased Acetylcholinesterase Activity at the Neuromuscular Junction of the Diaphragm during Sepsis
por: Liu, Hua, et al.
Publicado: (2017)

Reducing Ventilator-associated Brain Injury by Diaphragm Neurostimulation: Racking the Diaphragm to Protect the Brain?
por: Dres, Martin, et al.
Publicado: (2021)

Dexmedetomidine alleviated sepsis-induced myocardial ferroptosis and septic heart injury
por: Wang, Chunyan, et al.
Publicado: (2020)

Protective Effects of Dexmedetomidine on Sepsis-Induced Vascular Leakage by Alleviating Ferroptosis via Regulating Metabolic Reprogramming
por: She, Han, et al.
Publicado: (2021)

Dose-related effects of dexmedetomidine on sepsis-initiated lung injury in rats
por: Karabulut, Gülsüm, et al.
Publicado: (2021)

Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction
por: Morton, Aaron B., et al.
Publicado: (2018)

Sepsis Disrupts Mitochondrial Function and Diaphragm Morphology
por: Oliveira, Thamires Siqueira, et al.
Publicado: (2021)

Influence of Dexmedetomidine on Diaphragm Function and Postoperative Outcomes in ICU Patients with Mechanical Ventilation
por: Zhao, Chengda, et al.
Publicado: (2021)

Protective effect of methylprednisolone on ventilator-induced diaphragm dysfunction is dose dependent
por: Maes, K, et al.
Publicado: (2010)

Retracted: Influence of Dexmedetomidine on Diaphragm Function and Postoperative Outcomes in ICU Patients with Mechanical Ventilation
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Protective effects of dexmedetomidine in vital organ injury: crucial roles of autophagy
por: Zhao, Shankun, et al.
Publicado: (2022)

Administration of Dexmedetomidine Does Not Produce Long-Term Protective Effect on Testicular Damage Post Testicular Ischemia-Reperfusion Injury
por: Xiao, Jing, et al.
Publicado: (2021)

Effect of dexmedetomidine on tourniquet-induced skeletal muscle injury
por: Cheng, Wenjie, et al.
Publicado: (2023)

Neuregulin-1β Protects the Rat Diaphragm during Sepsis against Oxidative Stress and Inflammation by Activating the PI3K/Akt Pathway
por: Liu, Hua, et al.
Publicado: (2020)

Dexmedetomidine Protects against Ischemia and Reperfusion-Induced Kidney Injury in Rats
por: Bao, Naren, et al.
Publicado: (2020)

Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis
por: Sun, Yi-Bing, et al.
Publicado: (2019)

Dexmedetomidine Protects Against Traumatic Brain Injury-Induced Acute Lung Injury in Mice
por: Wang, Yuanyuan, et al.
Publicado: (2018)

Monitoring and preventing diaphragm injury
por: Heunks, Leo M.A., et al.
Publicado: (2015)

Treating traumatic injuries of the diaphragm
por: Dwivedi, Sankalp, et al.
Publicado: (2010)

Protective effects of dexmedetomidine on hypoxia/reoxygenation injury in cardiomyocytes by regulating the CHOP signaling pathway
por: Shi, Xiaoqiao, et al.
Publicado: (2020)

The role of spleen in the treatment of experimental lipopolysaccharide-induced sepsis with dexmedetomidine
por: Liu, Zhaoguo, et al.
Publicado: (2015)

Protective Effects of Glutamine and Leucine Supplementation on Sepsis-Induced Skeletal Muscle Injuries
por: Hou, Yu-Chen, et al.
Publicado: (2021)

The Effects of Dexmedetomidine on Secondary Acute Lung and Kidney Injuries in the Rat Model of Intra-Abdominal Sepsis
por: Koca, Uğur, et al.
Publicado: (2013)

Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis
por: Zhang, Qian, et al.
Publicado: (2023)

Dexmedetomidine may decrease the bupivacaine toxicity to heart
por: Jin, Zhousheng, et al.
Publicado: (2021)

Treatment with irbesatan may improve slit diaphragm alterations in rats with adriamycin-induced nephropathy
por: Wang, Na, et al.
Publicado: (2016)

Lung-protective ventilation worsens ventilator-induced diaphragm atrophy and weakness
por: Zhou, Xian-Long, et al.
Publicado: (2020)

Angiotensin 1‐7 protects against ventilator‐induced diaphragm dysfunction
por: Yoshihara, Toshinori, et al.
Publicado: (2021)

Dexmedetomidine may upregulate the expression of caveolin-1 in lung tissues of rats with sepsis and improve the short-term outcome
por: Zhang, Yun, et al.
Publicado: (2017)

Lung- and Diaphragm-Protective Ventilation by Titrating Inspiratory Support to Diaphragm Effort: A Randomized Clinical Trial
por: de Vries, Heder J., et al.
Publicado: (2022)

Protective Effects of Astragalus Polysaccharide on Sepsis-Induced Acute Kidney Injury
por: Sun, Jie, et al.
Publicado: (2021)

Dexmedetomidine improves the outcomes for pediatric severe sepsis with mechanical ventilation
por: Zhao, Chun, et al.
Publicado: (2023)

Mechanical ventilation preserves diaphragm mitochondrial function in a rat sepsis model
por: Eyenga, P., et al.
Publicado: (2021)

Dexmedetomidine preconditioning protects against lung injury induced by ischemia-reperfusion through inhibition of autophagy
por: Zhang, Wei, et al.
Publicado: (2017)

Lung and Diaphragm Protection during Noninvasive Respiratory Support
por: Spinelli, Elena, et al.
Publicado: (2020)

The role of calpains in ventilator-induced diaphragm atrophy
por: Zhu, Xiaoping, et al.
Publicado: (2017)

Organ-Protective Effects and the Underlying Mechanism of Dexmedetomidine
por: Bao, Naren, et al.
Publicado: (2020)

Dexmedetomidine preconditioning protects against lung injury in hemorrhagic shock rats
por: Zhang, Lei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_quav72sqsr5tk7hgdb077980j8