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A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts

Currently, studies connected with Computational Fluid Dynamic (CFD) techniques focus on assessing hemodynamic of blood flow in vessels in different conditions e.g. after stent-graft’s placement. The paper propose a novel method of standardization of results obtained from calculations of stent-grafts...

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Autores principales: Polanczyk, Andrzej, Podyma, Marek, Trebinski, Lukasz, Chrzastek, Jaroslaw, Zbicinski, Ireneusz, Stefanczyk, Ludomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830540/
https://www.ncbi.nlm.nih.gov/pubmed/27073907
http://dx.doi.org/10.1371/journal.pone.0153332
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author Polanczyk, Andrzej
Podyma, Marek
Trebinski, Lukasz
Chrzastek, Jaroslaw
Zbicinski, Ireneusz
Stefanczyk, Ludomir
author_facet Polanczyk, Andrzej
Podyma, Marek
Trebinski, Lukasz
Chrzastek, Jaroslaw
Zbicinski, Ireneusz
Stefanczyk, Ludomir
author_sort Polanczyk, Andrzej
collection PubMed
description Currently, studies connected with Computational Fluid Dynamic (CFD) techniques focus on assessing hemodynamic of blood flow in vessels in different conditions e.g. after stent-graft’s placement. The paper propose a novel method of standardization of results obtained from calculations of stent-grafts' “pushing forces” (cumulative WSS—Wall Shear Stress), and describes its usefulness in diagnostic process. AngioCT data from 27 patients were used to reconstruct 3D geometries of stent-grafts which next were used to create respective reference cylinders. We made an assumption that both the side surface and the height of a stent-graft and a reference cylinder were equal. The proposed algorithm in conjunction with a stent-graft “pushing forces” on an implant wall, allowed us to determine which spatial configuration of a stent-graft predispose to the higher risk of its migration. For stent-grafts close to cylindrical shape (shape factor φ close to 1) WSS value was about 267Pa, while for stent-grafts different from cylindrical shape (φ close to 2) WSS value was about 635Pa. It was also noticed that deformation in the stent-graft’s bifurcation part impaired blood flow hemodynamic. Concluding the proposed algorithm of standardization proved its usefulness in estimating the WSS values that may be useful in diagnostic process. Angular bends or tortuosity in bifurcations of an aortic implant should be considered in further studies of estimation of the risk of implantation failure.
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spelling pubmed-48305402016-04-22 A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts Polanczyk, Andrzej Podyma, Marek Trebinski, Lukasz Chrzastek, Jaroslaw Zbicinski, Ireneusz Stefanczyk, Ludomir PLoS One Research Article Currently, studies connected with Computational Fluid Dynamic (CFD) techniques focus on assessing hemodynamic of blood flow in vessels in different conditions e.g. after stent-graft’s placement. The paper propose a novel method of standardization of results obtained from calculations of stent-grafts' “pushing forces” (cumulative WSS—Wall Shear Stress), and describes its usefulness in diagnostic process. AngioCT data from 27 patients were used to reconstruct 3D geometries of stent-grafts which next were used to create respective reference cylinders. We made an assumption that both the side surface and the height of a stent-graft and a reference cylinder were equal. The proposed algorithm in conjunction with a stent-graft “pushing forces” on an implant wall, allowed us to determine which spatial configuration of a stent-graft predispose to the higher risk of its migration. For stent-grafts close to cylindrical shape (shape factor φ close to 1) WSS value was about 267Pa, while for stent-grafts different from cylindrical shape (φ close to 2) WSS value was about 635Pa. It was also noticed that deformation in the stent-graft’s bifurcation part impaired blood flow hemodynamic. Concluding the proposed algorithm of standardization proved its usefulness in estimating the WSS values that may be useful in diagnostic process. Angular bends or tortuosity in bifurcations of an aortic implant should be considered in further studies of estimation of the risk of implantation failure. Public Library of Science 2016-04-13 /pmc/articles/PMC4830540/ /pubmed/27073907 http://dx.doi.org/10.1371/journal.pone.0153332 Text en © 2016 Polanczyk et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Polanczyk, Andrzej
Podyma, Marek
Trebinski, Lukasz
Chrzastek, Jaroslaw
Zbicinski, Ireneusz
Stefanczyk, Ludomir
A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts
title A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts
title_full A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts
title_fullStr A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts
title_full_unstemmed A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts
title_short A Novel Attempt to Standardize Results of CFD Simulations Basing on Spatial Configuration of Aortic Stent-Grafts
title_sort novel attempt to standardize results of cfd simulations basing on spatial configuration of aortic stent-grafts
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830540/
https://www.ncbi.nlm.nih.gov/pubmed/27073907
http://dx.doi.org/10.1371/journal.pone.0153332
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