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Human CNS cultures exposed to HIV-1 gp120 reproduce dendritic injuries of HIV-1-associated dementia

HIV-1-associated dementia remains a common subacute to chronic central nervous system degeneration in adult and pediatric HIV-1 infected populations. A number of viral and host factors have been implicated including the HIV-1 120 kDa envelope glycoprotein (gp120). In human post-mortem studies using...

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Detalles Bibliográficos
Autores principales: Iskander, Sam, Walsh, Kimberley A, Hammond, Robert R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC483060/
https://www.ncbi.nlm.nih.gov/pubmed/15285795
http://dx.doi.org/10.1186/1742-2094-1-7