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Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies
The immune response plays a key role in enhancing the therapeutic activity of oncolytic virotherapies. However, to date, investigators have relied on inherent interactions between the virus and the immune system, often coupled to the expression of a single cytokine transgene. Recently, the importanc...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830920/ https://www.ncbi.nlm.nih.gov/pubmed/27050526 http://dx.doi.org/10.1016/j.celrep.2016.03.017 |