Cargando…

Structural and functional properties of prefibrillar α-synuclein oligomers

The deposition of fibrillar alpha-synuclein (α-syn) within inclusions (Lewy bodies and Lewy neurites) in neurons and glial cells is a hallmark of synucleinopathies. α-syn populates a variety of assemblies ranging from prefibrillar oligomeric species to fibrils whose specific contribution to neurodeg...

Descripción completa

Detalles Bibliográficos
Autores principales: Pieri, Laura, Madiona, Karine, Melki, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830946/
https://www.ncbi.nlm.nih.gov/pubmed/27075649
http://dx.doi.org/10.1038/srep24526

Ejemplares similares