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Structural and functional properties of prefibrillar α-synuclein oligomers
The deposition of fibrillar alpha-synuclein (α-syn) within inclusions (Lewy bodies and Lewy neurites) in neurons and glial cells is a hallmark of synucleinopathies. α-syn populates a variety of assemblies ranging from prefibrillar oligomeric species to fibrils whose specific contribution to neurodeg...
Autores principales: | Pieri, Laura, Madiona, Karine, Melki, Ronald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830946/ https://www.ncbi.nlm.nih.gov/pubmed/27075649 http://dx.doi.org/10.1038/srep24526 |
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