Molecular basis of the STIL coiled coil oligomerization explains its requirement for de-novo formation of centrosomes in mammalian cells

The STIL protein is essential for centriole replication and for the non-templated, de novo centriole biogenesis that is required for mammalian embryogenesis. Here we performed quantitative biophysical and structural analysis of the central short coiled coil domain (CCD) of STIL that is critical for...

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Detalles Bibliográficos
Autores principales: David, Ahuvit, Amartely, Hadar, Rabinowicz, Noa, Shamir, Mai, Friedler, Assaf, Izraeli, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830966/
https://www.ncbi.nlm.nih.gov/pubmed/27075531
http://dx.doi.org/10.1038/srep24296

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