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Facilitated receptor-recognition and enhanced bioactivity of bone morphogenetic protein-2 on magnesium-substituted hydroxyapatite surface

Biomaterial surface functionalized with bone morphogenetic protein-2 (BMP-2) is a promising approach to fabricating successful orthopedic implants/scaffolds. However, the bioactivity of BMP-2 on material surfaces is still far from satisfactory and the mechanism of related protein-surface interaction...

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Detalles Bibliográficos
Autores principales: Huang, Baolin, Yuan, Yuan, Li, Tong, Ding, Sai, Zhang, Wenjing, Gu, Yuantong, Liu, Changsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830968/
https://www.ncbi.nlm.nih.gov/pubmed/27075233
http://dx.doi.org/10.1038/srep24323