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The HER2 inhibitor TAK165 Sensitizes Human Acute Myeloid Leukemia Cells to Retinoic Acid-Induced Myeloid Differentiation by activating MEK/ERK mediated RARα/STAT1 axis

The success of all-trans retinoic acid (ATRA) in differentiation therapy for patients with acute promyelocytic leukemia (APL) highly encourages researches to apply this therapy to other types of acute myeloid leukemia (AML). However, AML, with the exception of APL, fails to respond to differentiatio...

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Detalles Bibliográficos
Autores principales:	Shao, Xuejing, Liu, Yujia, Li, Yangling, Xian, Miao, Zhou, Qian, Yang, Bo, Ying, Meidan, He, Qiaojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830980/ https://www.ncbi.nlm.nih.gov/pubmed/27074819 http://dx.doi.org/10.1038/srep24589

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