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Prognostic impact of mutation profiling in patients with stage II and III colon cancer

Development of colorectal cancer (CRC) associates with accumulation of genetic mutations include the epidermal growth factor receptor (EGFR) signaling pathway. However, whether mutations in KRAS together with downstream factors BRAF, PIK3CA and NRAS impact prognosis is still unclear for stage II-III...

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Detalles Bibliográficos
Autores principales:	Shen, Yinchen, Han, Xiaohong, Wang, Jianfei, Wang, Shuai, Yang, Hongying, Lu, Shih-Hsin, Shi, Yuankai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830995/ https://www.ncbi.nlm.nih.gov/pubmed/27074743 http://dx.doi.org/10.1038/srep24310

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