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Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda

BACKGROUND: In Uganda, few children with congenital heart diseases (CHD) benefit from early corrective cardiac surgery. These children are at high risk of developing heart failure and electrolyte imbalances; factors which increase their risk of developing arrhythmias. This study aimed to determine t...

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Autores principales: Batte, Anthony, Lwabi, Peter, Lubega, Sulaiman, Kiguli, Sarah, Nabatte, Violette, Karamagi, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831118/
https://www.ncbi.nlm.nih.gov/pubmed/27074797
http://dx.doi.org/10.1186/s12872-016-0243-1
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author Batte, Anthony
Lwabi, Peter
Lubega, Sulaiman
Kiguli, Sarah
Nabatte, Violette
Karamagi, Charles
author_facet Batte, Anthony
Lwabi, Peter
Lubega, Sulaiman
Kiguli, Sarah
Nabatte, Violette
Karamagi, Charles
author_sort Batte, Anthony
collection PubMed
description BACKGROUND: In Uganda, few children with congenital heart diseases (CHD) benefit from early corrective cardiac surgery. These children are at high risk of developing heart failure and electrolyte imbalances; factors which increase their risk of developing arrhythmias. This study aimed to determine the prevalence and factors associated with arrhythmias among children with congenital heart diseases receiving care at Mulago Hospital. METHODS: This was a cross-sectional study carried out from August 2013 to March 2014 at Mulago Hospital. Children were consecutively enrolled into the study. Standard 12-lead electrocardiograms (ECGs) were performed on 194 children with CHD (age range 10 days–15 years). Data was analysed using SPSS 16.0. RESULTS: Out of 194 children studied, 53/194 (27.3 %, 95 % CI 21.0 – 33.6) children had arrhythmias. Of the CHD children, 44/194 (22.7 %, 95 % CI 16.8 – 28.6) had first degree AV block while 9/194 (4.6 %, 95 % CI 1.7 – 7.6) children had either ectopic atrial rhythm, premature atrial contractions, junctional rhythm, complete atrioventricular (AV) dissociation or premature ventricular contractions. Children using digoxin were more likely to have first degree AV block (OR 3.75, 95 % CI 1.60–8.86) while those aged 5 years and below were less likely to have first degree AV block (OR 0.16, 95 % CI 0.07–0.37). CONCLUSION: Arrhythmias are common among children with CHD receiving care from Mulago Hospital. These are associated with digoxin use, child’s age and electrolyte imbalances; factors which can easily be assessed, managed and where possible modified in these children during their care.
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spelling pubmed-48311182016-04-15 Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda Batte, Anthony Lwabi, Peter Lubega, Sulaiman Kiguli, Sarah Nabatte, Violette Karamagi, Charles BMC Cardiovasc Disord Research Article BACKGROUND: In Uganda, few children with congenital heart diseases (CHD) benefit from early corrective cardiac surgery. These children are at high risk of developing heart failure and electrolyte imbalances; factors which increase their risk of developing arrhythmias. This study aimed to determine the prevalence and factors associated with arrhythmias among children with congenital heart diseases receiving care at Mulago Hospital. METHODS: This was a cross-sectional study carried out from August 2013 to March 2014 at Mulago Hospital. Children were consecutively enrolled into the study. Standard 12-lead electrocardiograms (ECGs) were performed on 194 children with CHD (age range 10 days–15 years). Data was analysed using SPSS 16.0. RESULTS: Out of 194 children studied, 53/194 (27.3 %, 95 % CI 21.0 – 33.6) children had arrhythmias. Of the CHD children, 44/194 (22.7 %, 95 % CI 16.8 – 28.6) had first degree AV block while 9/194 (4.6 %, 95 % CI 1.7 – 7.6) children had either ectopic atrial rhythm, premature atrial contractions, junctional rhythm, complete atrioventricular (AV) dissociation or premature ventricular contractions. Children using digoxin were more likely to have first degree AV block (OR 3.75, 95 % CI 1.60–8.86) while those aged 5 years and below were less likely to have first degree AV block (OR 0.16, 95 % CI 0.07–0.37). CONCLUSION: Arrhythmias are common among children with CHD receiving care from Mulago Hospital. These are associated with digoxin use, child’s age and electrolyte imbalances; factors which can easily be assessed, managed and where possible modified in these children during their care. BioMed Central 2016-04-13 /pmc/articles/PMC4831118/ /pubmed/27074797 http://dx.doi.org/10.1186/s12872-016-0243-1 Text en © Batte et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Batte, Anthony
Lwabi, Peter
Lubega, Sulaiman
Kiguli, Sarah
Nabatte, Violette
Karamagi, Charles
Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda
title Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda
title_full Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda
title_fullStr Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda
title_full_unstemmed Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda
title_short Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda
title_sort prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending mulago national referral hospital, uganda
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831118/
https://www.ncbi.nlm.nih.gov/pubmed/27074797
http://dx.doi.org/10.1186/s12872-016-0243-1
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