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Immunogenicity of Leishmania-derived hepatitis B small surface antigen particles exposing highly conserved E2 epitope of hepatitis C virus
BACKGROUND: Hepatitis C virus (HCV) infection is a major health problem worldwide, affecting an estimated 2–3 % of human population. An HCV vaccine, however, remains unavailable. High viral diversity poses a challenge in developing a vaccine capable of eliciting a broad neutralizing antibody respons...
Autores principales: | Czarnota, Anna, Tyborowska, Jolanta, Peszyńska-Sularz, Grażyna, Gromadzka, Beata, Bieńkowska-Szewczyk, Krystyna, Grzyb, Katarzyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831159/ https://www.ncbi.nlm.nih.gov/pubmed/27075377 http://dx.doi.org/10.1186/s12934-016-0460-4 |
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