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GERANYLGERANYLACETONE ATTENUATES CISPLATIN-INDUCED REDUCTIONS IN CELL VIABILITY BY SUPPRESSING THE ELEVATION OF INTRACELLULAR P53 CONTENT WITHOUT HEAT SHOCK PROTEIN INDUCTION

Geranylgeranylacetone (GGA) was originally used as an anti-ulcer drug to protect gastric mucosa from various stresses, and it is also known to induce heat shock proteins (HSPs), especially HSP70. However, it remains unclear how GGA affects cellular functions in the presence of anti-cancer drugs. We...

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Detalles Bibliográficos
Autores principales:	HASEGAWA, MOTOFUSA, ISHIGURO, KAZUHIRO, ANDO, TAKAFUMI, GOTO, HIDEMI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nagoya University 2012
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831257/ https://www.ncbi.nlm.nih.gov/pubmed/22515118

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