EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS

A massive extravasation of pegylated-liposomal doxorubicin (Doxil(®)) accidentally occurred, affecting the right forearm of a 54-year-old woman with metastatic ovarian cancer who was receiving an intravenous infusion of the drug. In accordance with the institutional guidelines for vesicant drugs, a...

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Autores principales: MITSUMA, AYAKO, SAWAKI, MASATAKA, SHIBATA, TAKASHI, MORITA, SACHI, INADA, MEGUMI, SHIMOKATA, TOMOYA, SUGISHITA, MIHOKO, KITAGAWA, KOICHI, SAWADA, MASAKI, NAWA, AKIHIRO, ANDO, YUICHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831265/
https://www.ncbi.nlm.nih.gov/pubmed/22515126
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author MITSUMA, AYAKO
SAWAKI, MASATAKA
SHIBATA, TAKASHI
MORITA, SACHI
INADA, MEGUMI
SHIMOKATA, TOMOYA
SUGISHITA, MIHOKO
KITAGAWA, KOICHI
SAWADA, MASAKI
NAWA, AKIHIRO
ANDO, YUICHI
author_facet MITSUMA, AYAKO
SAWAKI, MASATAKA
SHIBATA, TAKASHI
MORITA, SACHI
INADA, MEGUMI
SHIMOKATA, TOMOYA
SUGISHITA, MIHOKO
KITAGAWA, KOICHI
SAWADA, MASAKI
NAWA, AKIHIRO
ANDO, YUICHI
author_sort MITSUMA, AYAKO
collection PubMed
description A massive extravasation of pegylated-liposomal doxorubicin (Doxil(®)) accidentally occurred, affecting the right forearm of a 54-year-old woman with metastatic ovarian cancer who was receiving an intravenous infusion of the drug. In accordance with the institutional guidelines for vesicant drugs, a corticosteroid preparation was immediately injected subcutaneously into the surrounding tissues. Clobetasol propionate and an ice pack were then topically applied to the affected region. There were no serious complications at the extravasation site, such as tissue necrosis or severe pain, and only a transient erythema of the skin and desquamation remained after 2 months.
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spelling pubmed-48312652016-04-25 EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS MITSUMA, AYAKO SAWAKI, MASATAKA SHIBATA, TAKASHI MORITA, SACHI INADA, MEGUMI SHIMOKATA, TOMOYA SUGISHITA, MIHOKO KITAGAWA, KOICHI SAWADA, MASAKI NAWA, AKIHIRO ANDO, YUICHI Nagoya J Med Sci Case Report A massive extravasation of pegylated-liposomal doxorubicin (Doxil(®)) accidentally occurred, affecting the right forearm of a 54-year-old woman with metastatic ovarian cancer who was receiving an intravenous infusion of the drug. In accordance with the institutional guidelines for vesicant drugs, a corticosteroid preparation was immediately injected subcutaneously into the surrounding tissues. Clobetasol propionate and an ice pack were then topically applied to the affected region. There were no serious complications at the extravasation site, such as tissue necrosis or severe pain, and only a transient erythema of the skin and desquamation remained after 2 months. Nagoya University 2012-02 /pmc/articles/PMC4831265/ /pubmed/22515126 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
MITSUMA, AYAKO
SAWAKI, MASATAKA
SHIBATA, TAKASHI
MORITA, SACHI
INADA, MEGUMI
SHIMOKATA, TOMOYA
SUGISHITA, MIHOKO
KITAGAWA, KOICHI
SAWADA, MASAKI
NAWA, AKIHIRO
ANDO, YUICHI
EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS
title EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS
title_full EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS
title_fullStr EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS
title_full_unstemmed EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS
title_short EXTRAVASATION OF PEGYLATED-LIPOSOMAL DOXORUBICIN: FAVORABLE OUTCOME AFTER IMMEDIATE SUBCUTANEOUS ADMINISTRATION OF CORTICOSTEROIDS
title_sort extravasation of pegylated-liposomal doxorubicin: favorable outcome after immediate subcutaneous administration of corticosteroids
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831265/
https://www.ncbi.nlm.nih.gov/pubmed/22515126
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