Factors associated with sinus bradycardia during crizotinib treatment: a retrospective analysis of two large‐scale multinational trials (PROFILE 1005 and 1007)

Decreases in heart rate (HR) have been described in patients receiving crizotinib. We performed a large retrospective analysis of HR changes during crizotinib therapy. HRs from vital‐sign data for patients with anaplastic lymphoma kinase (ALK)‐positive nonsmall cell lung cancer enrolled in PROFILE 1...

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Detalles Bibliográficos
Autores principales: Ou, Sai‐Hong Ignatius, Tang, Yiyun, Polli, Anna, Wilner, Keith D., Schnell, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831279/
https://www.ncbi.nlm.nih.gov/pubmed/26823131
http://dx.doi.org/10.1002/cam4.622

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