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MicroRNA‐21 induces 5‐fluorouracil resistance in human pancreatic cancer cells by regulating PTEN and PDCD4

Pancreatic cancer patients are often resistant to chemotherapy treatment, which results in poor prognosis. The objective of this study was to delineate the mechanism by which miR‐21 induces drug resistance to 5‐fluorouracil (5‐FU) in human pancreatic cancer cells (PATU8988 and PANC‐1). We report tha...

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Detalles Bibliográficos
Autores principales:	Wei, Xueju, Wang, Weibin, Wang, Lanlan, Zhang, Yuanyuan, Zhang, Xian, Chen, Mingtai, Wang, Fang, Yu, Jia, Ma, Yanni, Sun, Guotao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831288/ https://www.ncbi.nlm.nih.gov/pubmed/26864640 http://dx.doi.org/10.1002/cam4.626

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