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Maximal exercise does not increase ventilation heterogeneity in healthy trained adults
The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise‐induced arterial hypoxemia (EIAH). Hea...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831321/ https://www.ncbi.nlm.nih.gov/pubmed/27044853 http://dx.doi.org/10.14814/phy2.12747 |
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author | Wrobel, Jeremy P. Ellis, Matthew J. Kee, Kirk Stuart‐Andrews, Christopher R. Thompson, Bruce R. |
author_facet | Wrobel, Jeremy P. Ellis, Matthew J. Kee, Kirk Stuart‐Andrews, Christopher R. Thompson, Bruce R. |
author_sort | Wrobel, Jeremy P. |
collection | PubMed |
description | The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise‐induced arterial hypoxemia (EIAH). Healthy trained adult males were prospectively assessed for ventilation heterogeneity using lung clearance index (LCI), S(cond), and S(acin) at baseline, postexercise and at recovery, using the multiple breath nitrogen washout technique. The maximal exercise bout consisted of a maximal, incremental cardiopulmonary exercise test at 25 watt increments. Eighteen subjects were recruited with mean ± SD age of 35 ± 9 years. There were no significant changes in LCI, S(cond), or S(acin) following exercise or at recovery. While there was an overall reduction in SpO(2) with exercise (99.3 ± 1 to 93.7 ± 3%, P < 0.0001), the reduction in SpO(2) was not associated with changes in LCI, S(cond) or S(acin). Ventilation heterogeneity is not increased following a maximal exercise bout in healthy trained adults. Furthermore, EIAH is not associated with changes in ventilation heterogeneity in healthy trained adults. |
format | Online Article Text |
id | pubmed-4831321 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-48313212016-04-20 Maximal exercise does not increase ventilation heterogeneity in healthy trained adults Wrobel, Jeremy P. Ellis, Matthew J. Kee, Kirk Stuart‐Andrews, Christopher R. Thompson, Bruce R. Physiol Rep Original Research The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise‐induced arterial hypoxemia (EIAH). Healthy trained adult males were prospectively assessed for ventilation heterogeneity using lung clearance index (LCI), S(cond), and S(acin) at baseline, postexercise and at recovery, using the multiple breath nitrogen washout technique. The maximal exercise bout consisted of a maximal, incremental cardiopulmonary exercise test at 25 watt increments. Eighteen subjects were recruited with mean ± SD age of 35 ± 9 years. There were no significant changes in LCI, S(cond), or S(acin) following exercise or at recovery. While there was an overall reduction in SpO(2) with exercise (99.3 ± 1 to 93.7 ± 3%, P < 0.0001), the reduction in SpO(2) was not associated with changes in LCI, S(cond) or S(acin). Ventilation heterogeneity is not increased following a maximal exercise bout in healthy trained adults. Furthermore, EIAH is not associated with changes in ventilation heterogeneity in healthy trained adults. John Wiley and Sons Inc. 2016-04-06 /pmc/articles/PMC4831321/ /pubmed/27044853 http://dx.doi.org/10.14814/phy2.12747 Text en © 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Wrobel, Jeremy P. Ellis, Matthew J. Kee, Kirk Stuart‐Andrews, Christopher R. Thompson, Bruce R. Maximal exercise does not increase ventilation heterogeneity in healthy trained adults |
title | Maximal exercise does not increase ventilation heterogeneity in healthy trained adults |
title_full | Maximal exercise does not increase ventilation heterogeneity in healthy trained adults |
title_fullStr | Maximal exercise does not increase ventilation heterogeneity in healthy trained adults |
title_full_unstemmed | Maximal exercise does not increase ventilation heterogeneity in healthy trained adults |
title_short | Maximal exercise does not increase ventilation heterogeneity in healthy trained adults |
title_sort | maximal exercise does not increase ventilation heterogeneity in healthy trained adults |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831321/ https://www.ncbi.nlm.nih.gov/pubmed/27044853 http://dx.doi.org/10.14814/phy2.12747 |
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