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Maximal exercise does not increase ventilation heterogeneity in healthy trained adults

The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise‐induced arterial hypoxemia (EIAH). Hea...

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Autores principales: Wrobel, Jeremy P., Ellis, Matthew J., Kee, Kirk, Stuart‐Andrews, Christopher R., Thompson, Bruce R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831321/
https://www.ncbi.nlm.nih.gov/pubmed/27044853
http://dx.doi.org/10.14814/phy2.12747
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author Wrobel, Jeremy P.
Ellis, Matthew J.
Kee, Kirk
Stuart‐Andrews, Christopher R.
Thompson, Bruce R.
author_facet Wrobel, Jeremy P.
Ellis, Matthew J.
Kee, Kirk
Stuart‐Andrews, Christopher R.
Thompson, Bruce R.
author_sort Wrobel, Jeremy P.
collection PubMed
description The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise‐induced arterial hypoxemia (EIAH). Healthy trained adult males were prospectively assessed for ventilation heterogeneity using lung clearance index (LCI), S(cond), and S(acin) at baseline, postexercise and at recovery, using the multiple breath nitrogen washout technique. The maximal exercise bout consisted of a maximal, incremental cardiopulmonary exercise test at 25 watt increments. Eighteen subjects were recruited with mean ± SD age of 35 ± 9 years. There were no significant changes in LCI, S(cond), or S(acin) following exercise or at recovery. While there was an overall reduction in SpO(2) with exercise (99.3 ± 1 to 93.7 ± 3%, P < 0.0001), the reduction in SpO(2) was not associated with changes in LCI, S(cond) or S(acin). Ventilation heterogeneity is not increased following a maximal exercise bout in healthy trained adults. Furthermore, EIAH is not associated with changes in ventilation heterogeneity in healthy trained adults.
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spelling pubmed-48313212016-04-20 Maximal exercise does not increase ventilation heterogeneity in healthy trained adults Wrobel, Jeremy P. Ellis, Matthew J. Kee, Kirk Stuart‐Andrews, Christopher R. Thompson, Bruce R. Physiol Rep Original Research The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise‐induced arterial hypoxemia (EIAH). Healthy trained adult males were prospectively assessed for ventilation heterogeneity using lung clearance index (LCI), S(cond), and S(acin) at baseline, postexercise and at recovery, using the multiple breath nitrogen washout technique. The maximal exercise bout consisted of a maximal, incremental cardiopulmonary exercise test at 25 watt increments. Eighteen subjects were recruited with mean ± SD age of 35 ± 9 years. There were no significant changes in LCI, S(cond), or S(acin) following exercise or at recovery. While there was an overall reduction in SpO(2) with exercise (99.3 ± 1 to 93.7 ± 3%, P < 0.0001), the reduction in SpO(2) was not associated with changes in LCI, S(cond) or S(acin). Ventilation heterogeneity is not increased following a maximal exercise bout in healthy trained adults. Furthermore, EIAH is not associated with changes in ventilation heterogeneity in healthy trained adults. John Wiley and Sons Inc. 2016-04-06 /pmc/articles/PMC4831321/ /pubmed/27044853 http://dx.doi.org/10.14814/phy2.12747 Text en © 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Wrobel, Jeremy P.
Ellis, Matthew J.
Kee, Kirk
Stuart‐Andrews, Christopher R.
Thompson, Bruce R.
Maximal exercise does not increase ventilation heterogeneity in healthy trained adults
title Maximal exercise does not increase ventilation heterogeneity in healthy trained adults
title_full Maximal exercise does not increase ventilation heterogeneity in healthy trained adults
title_fullStr Maximal exercise does not increase ventilation heterogeneity in healthy trained adults
title_full_unstemmed Maximal exercise does not increase ventilation heterogeneity in healthy trained adults
title_short Maximal exercise does not increase ventilation heterogeneity in healthy trained adults
title_sort maximal exercise does not increase ventilation heterogeneity in healthy trained adults
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831321/
https://www.ncbi.nlm.nih.gov/pubmed/27044853
http://dx.doi.org/10.14814/phy2.12747
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