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Inhibition on Apoptosis Induced by Elevated Hydrostatic Pressure in Retinal Ganglion Cell-5 via Laminin Upregulating β1-integrin/Focal Adhesion Kinase/Protein Kinase B Signaling Pathway

BACKGROUND: Glaucoma is a progressive optic neuropathy characterized by degeneration of neurons due to loss of retinal ganglion cells (RGCs). High intraocular pressure (HIOP), the main risk factor, causes the optic nerve damage. However, the precise mechanism of HIOP-induced RGC death is not yet com...

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Detalles Bibliográficos
Autores principales:	Li, Yi, Chen, Yan-Ming, Sun, Ming-Ming, Guo, Xiao-Dan, Wang, Ya-Chen, Zhang, Zhong-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831534/ https://www.ncbi.nlm.nih.gov/pubmed/27064044 http://dx.doi.org/10.4103/0366-6999.179785

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