Cargando…

A genetic variant in large tumor suppressor kinase 2 of Hippo signaling pathway contributes to prognosis of hepatocellular carcinoma

The Hippo pathway plays an important role in the development of hepatocellular carcinoma (HCC). The present study aimed at exploring the genetic variants of Hippo pathway-related genes and their association with HCC prognosis. A total of 331 HCC patients who tested positive for hepatitis B surface a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Lili, Wen, Juan, Zhao, Tingting, Hu, Zhibin, Song, Ci, Gu, Dongying, He, Mingliang, Lee, Nikki P, Xu, Zhi, Chen, Jinfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831600/ https://www.ncbi.nlm.nih.gov/pubmed/27110123 http://dx.doi.org/10.2147/OTT.S100699

Ejemplares similares

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
por: Serrano, Isabel, et al.
Publicado: (2013)

The prognostic impacts of TEA domain (TEAD) transcription factor polymorphisms in Chinese hepatocellular carcinoma patients
por: Xia, Haiyan, et al.
Publicado: (2017)

Expression quantitative trait loci for PAX8 contributes to the prognosis of hepatocellular carcinoma
por: Ma, Shijie, et al.
Publicado: (2017)

HBV mutations in EnhII/BCP/PC region contribute to the prognosis of hepatocellular carcinoma
por: Ge, Zijun, et al.
Publicado: (2019)

PML Surfs into HIPPO Tumor Suppressor Pathway
por: Strano, Sabrina, et al.
Publicado: (2013)

ACADL plays a tumor-suppressor role by targeting Hippo/YAP signaling in hepatocellular carcinoma
por: Zhao, Xiaofang, et al.
Publicado: (2020)

Hippo on the move: Tumor suppressor regulates adhesion and migration
por: Artemenko, Yulia, et al.
Publicado: (2013)

Inactivation of the Hippo tumor suppressor pathway promotes melanoma
por: Vittoria, Marc A., et al.
Publicado: (2022)

Clinical significance of ALDH2 rs671 polymorphism in esophageal cancer: evidence from 31 case-control studies
por: Zhao, Tingting, et al.
Publicado: (2015)

WW domain interactions regulate the Hippo tumor suppressor pathway
por: Salah, Z, et al.
Publicado: (2011)

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor
por: Martin, Daniel, et al.
Publicado: (2018)

Emerging role of the Hippo pathway in autophagy
por: Wang, Dongying, et al.
Publicado: (2020)

A genetic variant in pseudogene E2F3P1 contributes to prognosis of hepatocellular carcinoma
por: Pan, Yun, et al.
Publicado: (2014)

miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma
por: Liu, Angela M., et al.
Publicado: (2014)

MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma
por: Wang, Jian, et al.
Publicado: (2012)

Upregulation of liver kinase B1 predicts poor prognosis in hepatocellular carcinoma
por: Tan, Xiaolong, et al.
Publicado: (2018)

PTPRU, As A Tumor Suppressor, Inhibits Cancer Stemness By Attenuating Hippo/YAP Signaling Pathway
por: Gu, Jiayi, et al.
Publicado: (2019)

The Roles of NDR Protein Kinases in Hippo Signalling
por: Hergovich, Alexander
Publicado: (2016)

Activation mechanisms of the Hippo kinase signaling cascade
por: Bae, Sung Jun, et al.
Publicado: (2018)

Polymorphism in one-carbon metabolism pathway affects survival of gastric cancer patients: Large and comprehensive study
por: Zhao, Tingting, et al.
Publicado: (2015)

Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer
por: Vahid, Sepideh, et al.
Publicado: (2016)

Loss of the emei tumor suppressor promotes tumorigenesis via the JNK and Hippo pathway
por: Yang, Shuai, et al.
Publicado: (2022)

Survival benefit from S-1 as compared to Fluorouracil in Asian patients with advanced gastrointestinal cancer: A meta-analysis
por: Cao, Chunxiang, et al.
Publicado: (2014)

The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy
por: Klimek, Christina, et al.
Publicado: (2019)

Hepatic Hippo signaling inhibits development of hepatocellular carcinoma
por: Liu, Yuchen, et al.
Publicado: (2020)

AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol
por: Jagannathan, Radhika, et al.
Publicado: (2016)

MicroRNA miR-4709-3p targets Large Tumor Suppressor Kinase 2 (LATS2) and induces obstructive renal fibrosis through Hippo signaling
por: Jiang, Zexiang, et al.
Publicado: (2021)

Advances in prognostic and therapeutic targets for hepatocellular carcinoma and intrahepatic cholangiocarcinoma: The hippo signaling pathway
por: Mranda, Geofrey Mahiki, et al.
Publicado: (2022)

Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis
por: Liu, Lili, et al.
Publicado: (2012)

microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway
por: Mitamura, Takashi, et al.
Publicado: (2014)

Alcohol Interacts with Genetic Alteration of the Hippo Tumor Suppressor Pathway to Modulate Tissue Growth in Drosophila
por: Ilanges, Anoj, et al.
Publicado: (2013)

Ras Mitogen-activated Protein Kinase Signaling and Kinase Suppressor of Ras as Therapeutic Targets for Hepatocellular Carcinoma
por: Moon, Hyuk, et al.
Publicado: (2021)

Carboxyl-terminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma
por: Li, Weihua, et al.
Publicado: (2016)

Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress
por: Wang, Yang, et al.
Publicado: (2019)

Correction: microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway
por: Mitamura, Takashi, et al.
Publicado: (2014)

Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer
por: Sun, Min, et al.
Publicado: (2017)

Integrated screens uncover a cell surface tumor suppressor gene KIRREL involved in Hippo pathway
por: Wang, Chao, et al.
Publicado: (2022)

CORO7 functions as a scaffold protein for the core kinase complex assembly of the Hippo pathway
por: Park, Jina, et al.
Publicado: (2020)

Cyclin-dependent kinase 19 upregulation correlates with an unfavorable prognosis in hepatocellular carcinoma
por: Cai, Xiaopeng, et al.
Publicado: (2021)

α-Hederin Inhibits the Proliferation of Hepatocellular Carcinoma Cells via Hippo-Yes-Associated Protein Signaling Pathway
por: Chen, Tongqing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fr3lmfc4h93205bctfejhdba7s