Identification of BRCA1 Deficiency Using Multi-Analyte Estimation of BRCA1 and Its Repressors in FFPE Tumor Samples from Patients with Triple Negative Breast Cancer

PURPOSE: Apart from germ-line BRCA1-mutated breast cancers, a significant proportion of women with sporadic triple negative breast cancer (TNBC) sub-type are known to harbour varying levels of BRCA1-dysfuction. There is currently no established diagnostic method to identify these patients. METHODS:...

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Detalles Bibliográficos
Autores principales: Korlimarla, Aruna, Prabhu, Jyothi S., Remacle, Jose, Rajarajan, Savitha, Raja, Uma, C. E., Anupama, Srinath, B. S., Manjunath, Suraj, K. S., Gopinath, Correa, Marjorrie, M. S. N., Prasad, Sridhar, T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831669/
https://www.ncbi.nlm.nih.gov/pubmed/27077368
http://dx.doi.org/10.1371/journal.pone.0153113

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