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Cloning and Characterization of a Human Genomic Sequence that Alleviates Repeat-Induced Gene Silencing
Plasmids bearing a mammalian replication initiation region (IR) and a nuclear matrix attachment region (MAR) are spontaneously amplified in transfected mammalian cells, and such amplification generates chromosomal homogeneously staining regions (HSRs) or extrachromosomal double minutes (DMs). This m...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831671/ https://www.ncbi.nlm.nih.gov/pubmed/27078685 http://dx.doi.org/10.1371/journal.pone.0153338 |