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Exploiting syntactic and semantics information for chemical–disease relation extraction

Identifying chemical–disease relations (CDR) from biomedical literature could improve chemical safety and toxicity studies. This article proposes a novel syntactic and semantic information exploitation method for CDR extraction. The proposed method consists of a feature-based model, a tree kernel-ba...

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Autores principales: Zhou, Huiwei, Deng, Huijie, Chen, Long, Yang, Yunlong, Jia, Chen, Huang, Degen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831723/
https://www.ncbi.nlm.nih.gov/pubmed/27081156
http://dx.doi.org/10.1093/database/baw048
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author Zhou, Huiwei
Deng, Huijie
Chen, Long
Yang, Yunlong
Jia, Chen
Huang, Degen
author_facet Zhou, Huiwei
Deng, Huijie
Chen, Long
Yang, Yunlong
Jia, Chen
Huang, Degen
author_sort Zhou, Huiwei
collection PubMed
description Identifying chemical–disease relations (CDR) from biomedical literature could improve chemical safety and toxicity studies. This article proposes a novel syntactic and semantic information exploitation method for CDR extraction. The proposed method consists of a feature-based model, a tree kernel-based model and a neural network model. The feature-based model exploits lexical features, the tree kernel-based model captures syntactic structure features, and the neural network model generates semantic representations. The motivation of our method is to fully utilize the nice properties of the three models to explore diverse information for CDR extraction. Experiments on the BioCreative V CDR dataset show that the three models are all effective for CDR extraction, and their combination could further improve extraction performance. Database URL: http://www.biocreative.org/resources/corpora/biocreative-v-cdr-corpus/.
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spelling pubmed-48317232016-04-18 Exploiting syntactic and semantics information for chemical–disease relation extraction Zhou, Huiwei Deng, Huijie Chen, Long Yang, Yunlong Jia, Chen Huang, Degen Database (Oxford) Original Article Identifying chemical–disease relations (CDR) from biomedical literature could improve chemical safety and toxicity studies. This article proposes a novel syntactic and semantic information exploitation method for CDR extraction. The proposed method consists of a feature-based model, a tree kernel-based model and a neural network model. The feature-based model exploits lexical features, the tree kernel-based model captures syntactic structure features, and the neural network model generates semantic representations. The motivation of our method is to fully utilize the nice properties of the three models to explore diverse information for CDR extraction. Experiments on the BioCreative V CDR dataset show that the three models are all effective for CDR extraction, and their combination could further improve extraction performance. Database URL: http://www.biocreative.org/resources/corpora/biocreative-v-cdr-corpus/. Oxford University Press 2016-04-14 /pmc/articles/PMC4831723/ /pubmed/27081156 http://dx.doi.org/10.1093/database/baw048 Text en © The Author(s) 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zhou, Huiwei
Deng, Huijie
Chen, Long
Yang, Yunlong
Jia, Chen
Huang, Degen
Exploiting syntactic and semantics information for chemical–disease relation extraction
title Exploiting syntactic and semantics information for chemical–disease relation extraction
title_full Exploiting syntactic and semantics information for chemical–disease relation extraction
title_fullStr Exploiting syntactic and semantics information for chemical–disease relation extraction
title_full_unstemmed Exploiting syntactic and semantics information for chemical–disease relation extraction
title_short Exploiting syntactic and semantics information for chemical–disease relation extraction
title_sort exploiting syntactic and semantics information for chemical–disease relation extraction
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831723/
https://www.ncbi.nlm.nih.gov/pubmed/27081156
http://dx.doi.org/10.1093/database/baw048
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