Accelerated Lactate Dehydrogenase Activity Potentiates Osteoclastogenesis via NFATc1 Signaling

Osteoclasts seem to be metabolic active during their differentiation and bone-resorptive activation. However, the functional role of lactate dehydrogenase (LDH), a tetrameric enzyme consisting of an A and/or B subunit that catalyzes interconversion of pyruvate to lactate, in RANKL-induced osteoclast...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Heejin, Lee, Kyunghee, Kim, Jin Man, Kwon, So Hyun, Lee, Seoung Hoon, Lee, Soo Young, Jeong, Daewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831772/
https://www.ncbi.nlm.nih.gov/pubmed/27077737
http://dx.doi.org/10.1371/journal.pone.0153886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831772/
https://www.ncbi.nlm.nih.gov/pubmed/27077737
http://dx.doi.org/10.1371/journal.pone.0153886

Ejemplares similares