Cargando…
Structural comparison of the Caenorhabditis elegans and human Ndc80 complexes bound to microtubules reveals distinct binding behavior
During cell division, kinetochores must remain tethered to the plus ends of dynamic microtubule polymers. However, the molecular basis for robust kinetochore–microtubule interactions remains poorly understood. The conserved four-subunit Ndc80 complex plays an essential and direct role in generating...
Autores principales: | Wilson-Kubalek, Elizabeth M., Cheeseman, Iain M., Milligan, Ronald A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831874/ https://www.ncbi.nlm.nih.gov/pubmed/26941333 http://dx.doi.org/10.1091/mbc.E15-12-0858 |
Ejemplares similares
-
Orientation and structure of the Ndc80 complex on the microtubule lattice
por: Wilson-Kubalek, Elizabeth M., et al.
Publicado: (2008) -
Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80
por: Kern, David M, et al.
Publicado: (2017) -
Stable kinetochore‐microtubule attachment requires loop‐dependent Ndc80‐Ndc80 binding
por: Polley, Soumitra, et al.
Publicado: (2023) -
Multi-modal microtubule binding by the Ndc80 kinetochore complex
por: Alushin, Gregory M., et al.
Publicado: (2012) -
Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation
por: Sarangapani, Krishna K., et al.
Publicado: (2021)