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Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast

Cells maintain proteostasis by selectively recognizing and targeting misfolded proteins for degradation. In Saccharomyces cerevisiae, the Hsp70 nucleotide exchange factor Fes1 is essential for the degradation of chaperone-associated misfolded proteins by the ubiquitin-proteasome system. Here we show...

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Detalles Bibliográficos
Autores principales:	Gowda, Naveen Kumar Chandappa, Kaimal, Jayasankar Mohanakrishnan, Masser, Anna E., Kang, Wenjing, Friedländer, Marc R., Andréasson, Claes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831876/ https://www.ncbi.nlm.nih.gov/pubmed/26912797 http://dx.doi.org/10.1091/mbc.E15-10-0697

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