Cargando…

Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins

Depletion of microtubule (MT) regulators can initiate stable alterations in MT assembly rates that affect chromosome instability and mitotic spindle function, but the manner by which cellular MT assembly rates can stably increase or decrease is not understood. To investigate this phenomenon, we meas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wordeman, Linda, Decarreau, Justin, Vicente, Juan Jesus, Wagenbach, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831883/ https://www.ncbi.nlm.nih.gov/pubmed/26912793 http://dx.doi.org/10.1091/mbc.E15-11-0803

Ejemplares similares

MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment
por: Domnitz, Sarah B., et al.
Publicado: (2012)

A kinesin-13 mutant catalytically depolymerizes microtubules in ADP
por: Wagenbach, Michael, et al.
Publicado: (2008)

A tetrameric kinesin, Kif25, suppresses centrosome separation to establish proper spindle orientation
por: Decarreau, Justin, et al.
Publicado: (2017)

A new model for binding of kinesin 13 to curved microtubule protofilaments
por: Mulder, Anke M., et al.
Publicado: (2009)

Mitotic Centromere–associated Kinesin Is Important for Anaphase Chromosome Segregation
por: Maney, Todd, et al.
Publicado: (1998)

Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK
por: Cooper, Jeremy R., et al.
Publicado: (2009)

MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover
por: Wordeman, Linda, et al.
Publicado: (2007)

K-loop insertion restores microtubule depolymerizing activity of a “neckless” MCAK mutant
por: Ovechkina, Yulia, et al.
Publicado: (2002)

GTP-tubulin loves microtubule plus ends but marries the minus ends
por: Wordeman, Linda
Publicado: (2019)

Microtubule Targeting Agents in Disease: Classic Drugs, Novel Roles
por: Wordeman, Linda, et al.
Publicado: (2021)

MCAK associates with the tips of polymerizing microtubules
por: Moore, Ayana T., et al.
Publicado: (2005)

Motor-dependent microtubule disassembly driven by tubulin tyrosination
por: Peris, Leticia, et al.
Publicado: (2009)

Functional characterization of MCAK/Kif2C cancer mutations using high-throughput microscopic analysis
por: Wagenbach, Mike, et al.
Publicado: (2020)

Reconstitution of dynein transport to the microtubule plus end by kinesin
por: Roberts, Anthony J, et al.
Publicado: (2014)

Identification of key residues that regulate the interaction of kinesins with microtubule ends
por: Belsham, Hannah R., et al.
Publicado: (2019)

A microtubule polymerase cooperates with the kinesin-6 motor and a microtubule cross-linker to promote bipolar spindle assembly in the absence of kinesin-5 and kinesin-14 in fission yeast
por: Yukawa, Masashi, et al.
Publicado: (2017)

TIP150 interacts with and targets MCAK at the microtubule plus ends
por: Jiang, Kai, et al.
Publicado: (2009)

Loss of kinesin-14 results in aneuploidy via kinesin-5-dependent microtubule protrusions leading to chromosome cut
por: Syrovatkina, Viktoriya, et al.
Publicado: (2015)

Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14
por: Hentrich, Christian, et al.
Publicado: (2010)

Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding
por: Solon, April L., et al.
Publicado: (2021)

Activation of mitotic kinesin by microtubule bundling
por: Tomishige, Michio
Publicado: (2008)

Kinesin follows the microtubule's protofilament axis
Publicado: (1993)

Electrostatically Biased Binding of Kinesin to Microtubules
por: Grant, Barry J., et al.
Publicado: (2011)

Kinesin-5 is a microtubule polymerase
por: Chen, Yalei, et al.
Publicado: (2015)

Light Chain– dependent Regulation of Kinesin's Interaction with Microtubules
por: Verhey, Kristen J., et al.
Publicado: (1998)

Kinesin is bound with high affinity to squid axon organelles that move to the plus-end of microtubules
Publicado: (1992)

Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK
por: Shrestha, Roshan L., et al.
Publicado: (2013)

Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK
por: Shrestha, Roshan L., et al.
Publicado: (2013)

Opposing kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends
por: Meadows, John C, et al.
Publicado: (2018)

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target
por: Sanhaji, Mourad, et al.
Publicado: (2011)

Rapid Movements of Vimentin on Microtubule Tracks: Kinesin-dependent Assembly of Intermediate Filament Networks
por: Prahlad, Veena, et al.
Publicado: (1998)

Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains
Publicado: (1988)

Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization
por: Cao, Yujie, et al.
Publicado: (2020)

Microtubule minus end motors kinesin-14 and dynein drive nuclear congression in parallel pathways
por: Scheffler, Kathleen, et al.
Publicado: (2015)

The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition
por: Patel, Jennifer T., et al.
Publicado: (2016)

Kinesin-13s form rings around microtubules
por: Tan, Dongyan, et al.
Publicado: (2006)

Kinesin expands and stabilises the GDP-microtubule lattice
por: Peet, Daniel R., et al.
Publicado: (2018)

Parts list for a microtubule depolymerising kinesin
por: Friel, Claire T., et al.
Publicado: (2018)

Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow
por: Rankin, Kathleen E., et al.
Publicado: (2010)

Microtubule sliding activity of a kinesin-8 promotes spindle assembly and spindle length control
por: Su, Xiaolei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_v1rjf268p6be4bh0nskop59kua