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RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage–induced cell senescence

The coordination of cell cycle progression with the repair of DNA damage supports the genomic integrity of dividing cells. The function of many factors involved in DNA damage response (DDR) and the cell cycle depends on their Ran GTPase–regulated nuclear–cytoplasmic transport (NCT). The loading of R...

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Detalles Bibliográficos
Autores principales:	Cekan, Pavol, Hasegawa, Keisuke, Pan, Yu, Tubman, Emily, Odde, David, Chen, Jin-Qiu, Herrmann, Michelle A., Kumar, Sheetal, Kalab, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831887/ https://www.ncbi.nlm.nih.gov/pubmed/26864624 http://dx.doi.org/10.1091/mbc.E16-01-0025

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