H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report

Low frequency repetitive TMS (rTMS) of a cortical seizure focus is emerging as an antiepileptic treatment. While conventional rTMS stimulators activate only superficial cortical areas, reaching deep epileptic foci, for example in temporal lobe epilepsy (TLE), is possible using specially designed H-c...

Descripción completa

Detalles Bibliográficos
Autores principales: Gersner, R., Oberman, L., Sanchez, M.J., Chiriboga, N., Kaye, H.L., Pascual-Leone, A., Libenson, M., Roth, Y., Zangen, A., Rotenberg, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832041/
https://www.ncbi.nlm.nih.gov/pubmed/27114902
http://dx.doi.org/10.1016/j.ebcr.2016.03.001
_version_ 1782427181623803904
author Gersner, R.
Oberman, L.
Sanchez, M.J.
Chiriboga, N.
Kaye, H.L.
Pascual-Leone, A.
Libenson, M.
Roth, Y.
Zangen, A.
Rotenberg, A.
author_facet Gersner, R.
Oberman, L.
Sanchez, M.J.
Chiriboga, N.
Kaye, H.L.
Pascual-Leone, A.
Libenson, M.
Roth, Y.
Zangen, A.
Rotenberg, A.
author_sort Gersner, R.
collection PubMed
description Low frequency repetitive TMS (rTMS) of a cortical seizure focus is emerging as an antiepileptic treatment. While conventional rTMS stimulators activate only superficial cortical areas, reaching deep epileptic foci, for example in temporal lobe epilepsy (TLE), is possible using specially designed H-coils. We report the results of rTMS in a young adult with pharmacoresistant bilateral TLE who underwent three courses (of 10, 15, and 30 daily sessions) of unilateral rTMS over the hemisphere from which seizures originated most often. Seizure frequency was assessed before and after each block of rTMS sessions, as was the tolerability of the procedure. Seizure frequency declined significantly, by 50 to 70% following each rTMS course. All sessions were well-tolerated.
format Online
Article
Text
id pubmed-4832041
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-48320412016-04-25 H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report Gersner, R. Oberman, L. Sanchez, M.J. Chiriboga, N. Kaye, H.L. Pascual-Leone, A. Libenson, M. Roth, Y. Zangen, A. Rotenberg, A. Epilepsy Behav Case Rep Case Report Low frequency repetitive TMS (rTMS) of a cortical seizure focus is emerging as an antiepileptic treatment. While conventional rTMS stimulators activate only superficial cortical areas, reaching deep epileptic foci, for example in temporal lobe epilepsy (TLE), is possible using specially designed H-coils. We report the results of rTMS in a young adult with pharmacoresistant bilateral TLE who underwent three courses (of 10, 15, and 30 daily sessions) of unilateral rTMS over the hemisphere from which seizures originated most often. Seizure frequency was assessed before and after each block of rTMS sessions, as was the tolerability of the procedure. Seizure frequency declined significantly, by 50 to 70% following each rTMS course. All sessions were well-tolerated. Elsevier 2016-03-16 /pmc/articles/PMC4832041/ /pubmed/27114902 http://dx.doi.org/10.1016/j.ebcr.2016.03.001 Text en © 2016 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Gersner, R.
Oberman, L.
Sanchez, M.J.
Chiriboga, N.
Kaye, H.L.
Pascual-Leone, A.
Libenson, M.
Roth, Y.
Zangen, A.
Rotenberg, A.
H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report
title H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report
title_full H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report
title_fullStr H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report
title_full_unstemmed H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report
title_short H-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: A case report
title_sort h-coil repetitive transcranial magnetic stimulation for treatment of temporal lobe epilepsy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832041/
https://www.ncbi.nlm.nih.gov/pubmed/27114902
http://dx.doi.org/10.1016/j.ebcr.2016.03.001
work_keys_str_mv AT gersnerr hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT obermanl hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT sanchezmj hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT chiribogan hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT kayehl hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT pascualleonea hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT libensonm hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT rothy hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT zangena hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport
AT rotenberga hcoilrepetitivetranscranialmagneticstimulationfortreatmentoftemporallobeepilepsyacasereport

Ejemplares similares